Promethazine Hcl/codeine Phosphate 6.25mg-10mg/5ml Syrup, Price Each Per Bottle!



Generic Phenergan With Codeine

PROMETHAZINE is a cough suppressant and an antihistamine. It helps to stop or reduce coughing due to colds or allergies. This medicine will not treat an infection. Compare opioid / phenothiazine combinations.


Respiratory Depression in kids

The combination of promethazine hydrochloride and codeine phosphate is contraindicated in paediatric patients less than six years of age. Concomitant administration of promethazine product with different metabolic process depressants has an association with respiratory depression, and sometimes death, in paediatric patients.

Postmarketing cases of respiratory depression, as well as fatalities, are reported with use of promethazine hydrochloride in paediatric patients but two years older. The large amount of weight-based doses of promethazine hydrochloride have resulted in respiratory depression in these patients.

Death associated with Ultra-Rapid Metabolism of codeine to morphine

Respiratory depression and even death have occurred in kids. WHO received codeine following extirpation and/or adenoidectomy and had proof of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

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